Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 14/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28207563 | 0.92 | IDE (0.42) | IDEHTR6DRD2HTR1AHTR1D | |
| SCHEMBL19971345 | 0.88 | IDE (0.43) | IDEHTR6DRD2HTR1AHTR1D | |
| SCHEMBL19971398 | 0.84 | PDE4A (0.40) | IDEHTR6DRD2 | |
| SCHEMBL19971357 | 0.81 | IDE (0.39) | IDEHTR6 | |
| SCHEMBL28068051 | 0.80 | IDE (0.41) | IDEHTR6 | |
| SCHEMBL16619302 | 0.80 | HTR6 (0.44) | IDEHTR6DRD2HTR1AHTR1D | |
| SCHEMBL28068088 | 0.77 | HTR6 (0.36) | IDEHTR6 | |
| SCHEMBL16626633 | 0.77 | HTR6 (0.38) | IDEHTR6DRD2HTR1AHTR1D | |
| SCHEMBL19971450 | 0.76 | POLB (0.36) | IDEHTR6 | |
| SCHEMBL4772155 | 0.74 | HTR6 (0.47) | HTR6DRD2HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | claimed |