Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096533 | 0.87 | CDK2 (0.49) | MAP2K1PDGFRACDK5TYRO3KMT2A | |
| SCHEMBL7522675 | 0.83 | ALDH1A1 (0.44) | PDGFRACDK5TYRO3KMT2ACDK2 | |
| SCHEMBL25742134 | 0.82 | PDGFRA (0.40) | MAP2K1MAP2K2PDGFRACDK5TYRO3 | |
| SCHEMBL7504662 | 0.81 | KMT2A (0.40) | PDGFRACDK5TYRO3KMT2AKDM4E | |
| SCHEMBL497718 | 0.81 | NR4A2 (0.63) | KMT2AKDM4ENR4A2MAPTALDH1A1 | |
| SCHEMBL30568918 | 0.81 | IDO1 (0.54) | MAP2K1MAP2K2KMT2AKDM4ECDK2 | |
| SCHEMBL29164497 | 0.80 | HTT (0.64) | PDGFRACDK5TYRO3KMT2AKDM4E | |
| SCHEMBL2425287 | 0.79 | NR4A2 (0.46) | KMT2AKDM4ECDK2NR4A2MAPT | |
| SCHEMBL25742143 | 0.79 | CDK2 (0.38) | MAP2K1MAP2K2PDGFRACDK5TYRO3 | |
| SCHEMBL23362197 | 0.78 | LMNA (0.48) | MAP2K1KMT2AKDM4ECDK2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |