SCHEMBL19971952

SCHEMBL19971952

Fc1cccc(I)c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.44
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
ALDH1A1 P00352 1/20 0.35
SLC22A2 O15244 1/20 0.34
SLC22A1 O15245 1/20 0.34
SLC22A3 O75751 1/20 0.34
SLC6A4 P31645 1/20 0.34
NFE2L2 Q16236 1/20 0.34
TYMP P19971 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
AR P10275 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22928191 0.83 TTR (0.37) TTRLMNANFE2L2ACHECASP3
SCHEMBL5390122 0.83 TTR (0.58) TTRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL18920518 0.81 NPC1 (0.50) TTRCYP1A2CYP3A4CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL30833257 0.80 TTR (0.56) TTRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL1768313 0.77 KCNN4 (0.41) TTRNFE2L2ACHECASP3SENP8
SCHEMBL4612869 0.74 ALDH1A1 (0.41) HTTLMNAMAPTALDH1A1ESR1
SCHEMBL5066123 0.74 TTR (0.45) TTRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL3620806 0.73 TTR (0.48) TTRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL18939793 0.73 TTR (0.35) TTRLMNACASP3SENP8SENP7
SCHEMBL30476137 0.73 CYP2A6 (0.44) CYP1A2HTTLMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083317-A1 ADDITIVE COMPOSITION FOR LITHIUM BATTERY ELECTROLYTE, ORGANIC ELECTROLYTE INCLUDING THE SAME, AND LITHIUM BATTERY INCLUDING THE ADDITIVE COMPOSITION SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed