SCHEMBL19973027

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15254389	0.77	CYP1A2 (0.48)	PDK2ALDH1A1CYP1A2CHRM2OPRM1
	SCHEMBL15254386	0.77	CYP1A2 (0.48)	PDK2ALDH1A1CYP1A2CHRM2OPRM1
	SCHEMBL31712163	0.76	GAA (0.55)	GAAALDH1A1CYP1A2CYP2C9MEN1
	SCHEMBL2077117	0.76	GAA (0.55)	GAAALDH1A1CYP1A2CYP2C9MEN1
	SCHEMBL22201152	0.75	ACHE (0.52)	ALDH1A1CYP1A2CHRM2OPRM1DDB1
	SCHEMBL22190395	0.75	ACHE (0.52)	ALDH1A1CYP1A2CHRM2OPRM1DDB1
	SCHEMBL24753894	0.73	GAA (0.51)	GAAALDH1A1CYP1A2CYP2C9MEN1
	SCHEMBL13743062	0.73	GAA (0.47)	GAAALDH1A1CYP1A2CHRM2TDP1
	SCHEMBL2078273	0.72	GAA (0.50)	GAAALDH1A1CYP1A2TDP1CYP2C9
	SCHEMBL31330856	0.71	CHRM3 (0.46)	GAAALDH1A1CYP1A2CHRM2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.