Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.57 |
| ▸ | MARK3 | P27448 | 1/20 | 0.57 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 8/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98133 | 0.85 | HSD17B10 (0.38) | CDK2HSP90AA1CHEK1AURKAPDPK1 | |
| Hypoxanthine SCHEMBL4367641 | 0.83 | LMNA (0.39) | CDK2CHEK1PDPK1LRRK2HSD17B10 | |
| SCHEMBL9396874 | 0.83 | HTT (0.36) | CDK2HSP90AA1CHEK1AURKAPDPK1 | |
| Dimethyladenine SCHEMBL10617856 | 0.82 | CDK2 (0.61) | CDK2HSP90AA1CHEK1AURKAPDPK1 | |
| Adenine SCHEMBL593934 | 0.82 | PI4KA (0.54) | CDK2CHEK1PDPK1LRRK2HSD17B10 | |
| SCHEMBL9142303 | 0.82 | LMNA (0.38) | CDK2CHEK1PDPK1LRRK2HSD17B10 | |
| Mercaptopurine Anhydrous SCHEMBL1998389 | 0.82 | LMNA (0.38) | CDK2CHEK1PDPK1LRRK2HSD17B10 | |
| SCHEMBL4202116 | 0.82 | CYP3A4 (0.45) | CDK2HSD17B10HTTSMN1; SMN2LMNA | |
| Dimethyladenine SCHEMBL152594 | 0.75 | LRRK2 (1.00) | CDK2HSP90AA1CHEK1AURKAPDPK1 | |
| Dimethyladenine SCHEMBL29349831 | 0.75 | LRRK2 (1.00) | CDK2HSP90AA1CHEK1AURKAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516637-B1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | PLASMIA BIOTECH S L (ES) | 2016-04-20 | — | — | EP | disclosed |
| US-8759034-B2 | Thermostable biocatalyst combination for nucleoside synthesis | PLASMIA BIOTECH, S.L. (ES) | 2014-06-24 | — | — | US | disclosed |
| US-20130337547-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | BRILL ENGINES, S.L. (ES) | 2013-12-19 | — | — | US | disclosed |
| US-8512997-B2 | Thermostable biocatalyst combination for nucleoside synthesis | PLASMIA BIOTECH, S.L. (ES) | 2013-08-20 | — | — | US | disclosed |
| EP-2516637-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | Plasmia Biotech, S.L. (ES) | 2012-10-31 | — | — | EP | disclosed |
| US-20120264175-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | BRILL ENGINES, S.L. (ES) | 2012-10-18 | — | — | US | disclosed |
| WO-2011076894-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S.A. (ES) | 2011-06-30 | — | — | WO | disclosed |
| EP-2338985-A1 | Thermostable biocatalyst combination for nucleoside synthesis | Institut Univ. de Ciència i Tecnologia, s.a. (ES) | 2011-06-29 | — | — | EP | disclosed |