Hypoxanthine

Hypoxanthine

SCHEMBL4367641

OC[C@H]1OC[C@H](O)[C@@H]1O.Oc1ncnc2nc[nH]c12

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.39
HTT P42858 4/20 0.39
CYP3A4 P08684 1/20 0.37
HSD17B10 Q99714 3/20 0.36
AKT2 P31751 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
CHEK1 O14757 2/20 0.35
PI4KA P42356 2/20 0.35
PI4K2B Q8TCG2 2/20 0.35
PI4K2A Q9BTU6 2/20 0.35
PI4KB Q9UBF8 2/20 0.35
DRD3 P35462 1/20 0.35
XDH P47989 1/20 0.35
LRRK2 Q5S007 1/20 0.35
CDK2 P24941 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP1A2 P05177 2/20 0.34
CDK1 P06493 1/20 0.34
PAK1 Q13153 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9396874 0.87 HTT (0.36) LMNAHTTCYP3A4HSD17B10AKT2
Adenine SCHEMBL593934 0.86 PI4KA (0.54) LMNAHTTCYP3A4HSD17B10AKT2
Mercaptopurine Anhydrous SCHEMBL1998389 0.86 LMNA (0.38) LMNAHTTCYP3A4HSD17B10AKT2
SCHEMBL98133 0.86 HSD17B10 (0.38) LMNAHTTCYP3A4HSD17B10ALOX15
SCHEMBL9142303 0.86 LMNA (0.38) LMNAHTTCYP3A4HSD17B10ALOX15
SCHEMBL4202116 0.83 CYP3A4 (0.45) LMNAHTTCYP3A4HSD17B10TSHR
Dimethyladenine SCHEMBL1997329 0.83 CDK2 (0.57) LMNAHTTCYP3A4HSD17B10ALOX15
Purine SCHEMBL4378871 0.78 TREH (0.33)
2,6-Diaminopurine SCHEMBL443468 0.76 PDPK1 (0.55) CDK2CDK1PDPK1
Hypoxanthine SCHEMBL25382 0.74 LMNA (0.57) LMNAHTTCYP3A4HSD17B10AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109868309-A Single stranded DNA amplification method based on universal base replacement insertion 厦门市安美捷生物工程有限公司 2019-06-11 CN claimed
CN-109852727-A HBV-cccDNA detection method and kit based on universal base replacement insertion 厦门市安美捷生物工程有限公司 2019-06-07 CN claimed
CN-103484458-A Oligonucleotide sequence containing universal base and application thereof to DNA hybridization analysis UNIV SOUTHEAST 2014-01-01 CN claimed
US-20250257380-A1 METHOD FOR TEMPLATE-FREE DE NOVO SYNTHESIS OF LONG-CHAIN NUCLEIC ACID, AND USE THEREOF SHANGHAI TYPING BIOSCIENCE CO., LTD. (CN) 2025-08-14 US disclosed
EP-4582550-A1 METHOD FOR TEMPLATE-FREE DE NOVO SYNTHESIS OF LONG-CHAIN NUCLEIC ACID, AND USE THEREOF Shanghai Typing Bioscience Co., Ltd. (CN) 2025-07-09 EP disclosed
CN-105219865-B A kind of method for nucleic acid sequencing based on three-colour immunofiuorescence 东南大学 2018-08-21 CN disclosed
CN-108318594-A A kind of method that liquid chromatography tandem mass spectrometry measures activity of adenosine deaminase and screens its inhibitor 上海中医药大学 2018-07-24 CN disclosed
CN-108245500-A Royal jelly acid is preparing the purposes in treating the raised disease medicine of activity of adenosine deaminase 上海中医药大学 2018-07-06 CN disclosed
CN-108096387-A One group of Chinese medical extract with adenosine deaminase inhibitory activity and its application 上海中医药大学 2018-06-01 CN disclosed
CN-105219865-A A kind of method for nucleic acid sequencing based on three-colour immunofiuorescence UNIV SOUTHEAST 2016-01-06 CN disclosed
CN-102516337-B 3'sulfo-2'deoxyribose-3'nitro pyrrole phosphoramidite monomer, synthetic method and application thereof UNIV SOUTHEAST 2014-07-02 CN disclosed
CN-103484458-A Oligonucleotide sequence containing universal base and application thereof to DNA hybridization analysis UNIV SOUTHEAST 2014-01-01 CN disclosed
CN-102516337-A 3'sulfo-2'deoxyribose-3'nitro pyrrole phosphoramidite monomer, synthetic method and application thereof UNIV SOUTHEAST 2012-06-27 CN disclosed
CN-102180926-A Monomers of 3'thio-hypoxanthine deoxyribonucleoside phosphoramidite and application thereof UNIV SOUTHEAST 2011-09-14 CN disclosed
US-20090186358-A1 Pathway Analysis of Cell Culture Phenotypes and Uses Thereof WYETH (US) 2009-07-23 US disclosed