Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MGAM | O43451 | 2/20 | 0.55 |
| ▸ | SI | P14410 | 2/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19973399 | 1.00 | KMT2A (0.58) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL19973397 | 0.92 | KMT2A (0.64) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL19973396 | 0.92 | KMT2A (0.64) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL19973394 | 0.90 | GAA (0.56) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL19973395 | 0.90 | GAA (0.56) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL19973941 | 0.90 | KMT2A (0.74) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL19973942 | 0.90 | KMT2A (0.74) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL21273590 | 0.89 | KMT2A (0.70) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL19982166 | 0.88 | KMT2A (0.68) | KMT2AMEN1GAAMGAMSI | |
| SCHEMBL21273523 | 0.88 | KMT2A (0.68) | KMT2AMEN1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256502-A1 | ORGANIC COMPOUNDS | HOX THERAPEUTICS LIMITED (GB) | 2019-08-22 | — | — | US | disclosed |
| WO-2018051114-A1 | ORGANIC COMPOUNDS | HOX THERAPEUTICS LIMITED (GB) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256502-A1 | ORGANIC COMPOUNDS | POU2F1, BRIX1, PAX3 | KMT2A 702/4885MEN1 3544/4885GAA 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.