Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144061 | 0.80 | CHRM2 (0.38) | MEN1ALDH1A1KMT2ACHRM2CHRM1 | |
| SCHEMBL143165 | 0.80 | CHRM2 (0.38) | MEN1ALDH1A1KMT2ACHRM2CHRM1 | |
| SCHEMBL4767709 | 0.69 | CHRM2 (0.38) | MEN1ALDH1A1KMT2ACHRM2CHRM1 | |
| SCHEMBL28481839 | 0.69 | CHRM2 (0.30) | CHRM2CHRM1CHRM3 | |
| SCHEMBL25348441 | 0.67 | ALDH1A1 (0.38) | MEN1ALDH1A1TSHRKMT2ACHRM2 | |
| SCHEMBL31667788 | 0.67 | NR1H2 (0.37) | CHRM2CHRM1CHRM3GPR119DDB1 | |
| SCHEMBL30782513 | 0.67 | ALDH1A1 (0.38) | MEN1ALDH1A1TSHRKMT2ACHRM2 | |
| SCHEMBL24069211 | 0.66 | CHRM2 (0.44) | CHRM2CHRM1CHRM3GPR119DDB1 | |
| SCHEMBL29519744 | 0.66 | CHRM2 (0.41) | CHRM2CHRM1CHRM3GPR119DDB1 | |
| SCHEMBL28735688 | 0.66 | CHRM2 (0.41) | CHRM2CHRM1CHRM3GPR119DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512849-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050510-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |