Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782513 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ATSHRCHRM2 | |
| SCHEMBL25349102 | 0.86 | MEN1 (0.36) | ALDH1A1MEN1KMT2ATSHRCHRM2 | |
| SCHEMBL25348801 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ATSHRCHRM2 | |
| SCHEMBL25348423 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ATSHRCHRM2 | |
| SCHEMBL25348886 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ATSHRCHRM2 | |
| SCHEMBL13125666 | 0.85 | CHRM2 (0.39) | ALDH1A1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL6026752 | 0.85 | CHRM2 (0.39) | ALDH1A1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL974483 | 0.85 | CHRM2 (0.39) | ALDH1A1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL4370463 | 0.85 | CHRM2 (0.39) | ALDH1A1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL6026756 | 0.85 | CHRM2 (0.39) | ALDH1A1CHRM2CHRM1CHRM3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151621-A1 | COMPOUND HAVING ANTI-KRAS MUTANT TUMOR ACTIVITY | 泰励生物科技（上海）有限公司 | 2023-08-17 | — | — | WO | disclosed |