Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975114 | 0.92 | HRH3 (0.42) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL19974659 | 0.79 | MIF (0.41) | KMT2AHTTSMN1; SMN2TDP1HRH3 | |
| SCHEMBL15059972 | 0.77 | EPHX1 (0.50) | SMN1; SMN2HRH3HRH4TSHREPHX1 | |
| SCHEMBL19974692 | 0.73 | HRH4 (0.45) | HRH3HTR3AHRH4MAPTHPGD | |
| SCHEMBL29020255 | 0.72 | POLB (0.49) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL6662519 | 0.69 | HRH3 (0.75) | KMT2ASMN1; SMN2HRH3HTR3AHRH4 | |
| SCHEMBL30186773 | 0.69 | KMT2A (0.44) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL11167639 | 0.68 | PAX8 (0.45) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL11169197 | 0.68 | PAX8 (0.45) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL11162586 | 0.68 | PAX8 (0.45) | KMT2AHTTSMN1; SMN2TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512840-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | Tseng, Yufeng, Jane (US) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018053161-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | NATIONAL TAIWAN UNIVERSITY (TW) | 2018-03-22 | — | — | WO | disclosed |