Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975547 | 0.74 | HRH3 (0.43) | HRH4HRH3 | |
| SCHEMBL19974772 | 0.73 | KMT2A (0.43) | HRH4HTR3AMAPTHRH3HPGD | |
| SCHEMBL19974760 | 0.71 | HRH3 (0.40) | HRH4MAPTHRH3ALDH1A1IDO1 | |
| SCHEMBL19975114 | 0.70 | HRH3 (0.42) | HRH4MAPTHRH3ALDH1A1 | |
| SCHEMBL15059972 | 0.70 | EPHX1 (0.50) | HRH4HRH3ALDH1A1 | |
| SCHEMBL19974645 | 0.69 | MEN1 (0.38) | MAPTHRH3ALDH1A1 | |
| SCHEMBL28006498 | 0.68 | KLK7 (0.56) | ALDH1A1HPGD | |
| SCHEMBL27673261 | 0.68 | HRH4 (0.36) | HRH4MAPTHRH3ALDH1A1 | |
| SCHEMBL30799954 | 0.68 | HPGD (0.48) | MAPTHPGD | |
| SCHEMBL21396239 | 0.67 | KLK7 (0.51) | MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512840-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | Tseng, Yufeng, Jane (US) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018053161-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | NATIONAL TAIWAN UNIVERSITY (TW) | 2018-03-22 | — | — | WO | disclosed |