SCHEMBL19974938

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19975143	0.89	PTGIR (0.43)	SMN1; SMN2NPC1RAB9APTGIRALDH1A1
	SCHEMBL19975134	0.88	PTGIR (0.40)	SMN1; SMN2NPC1RAB9APTGIRALDH1A1
	SCHEMBL19975274	0.88	PTGIR (0.41)	PTGIRALDH1A1GAAF10PRSS1
	SCHEMBL19975062	0.86	ALDH1A1 (0.48)	SMN1; SMN2PTGIRALDH1A1GAAL3MBTL1
	SCHEMBL28315915	0.86	F10 (0.39)	SMN1; SMN2ALDH1A1GAAL3MBTL1F10
	SCHEMBL19974728	0.83	BCHE (0.42)	SMN1; SMN2PTGIRALDH1A1GAAL3MBTL1
	SCHEMBL19975353	0.83	BCHE (0.45)	SMN1; SMN2ALDH1A1GAAL3MBTL1MEN1
	SCHEMBL19974925	0.83	MEN1 (0.39)	SMN1; SMN2PTGIRALDH1A1GAAL3MBTL1
	SCHEMBL21176166	0.82	BCHE (0.46)	SMN1; SMN2ALDH1A1GAAL3MBTL1MEN1
	SCHEMBL28316641	0.81	SMN1; SMN2 (0.45)	SMN1; SMN2NPC1RAB9APTGIRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.