SCHEMBL19974960

SCHEMBL19974960

CC(C(O)C(=O)NCC1CC1)N(C=O)c1ccccc1F

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 3/20 0.41
ALDH1A1 P00352 2/20 0.40
F10 P00742 2/20 0.36
PRSS1 P07477 2/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19974932 0.88 L3MBTL1 (0.38) ALDH1A1F10PRSS1KMT2AMEN1
SCHEMBL19974925 0.87 MEN1 (0.39) PTGIRALDH1A1F10PRSS1KMT2A
SCHEMBL19975274 0.85 PTGIR (0.41) PTGIRALDH1A1F10PRSS1KMT2A
SCHEMBL19975415 0.85 HPGD (0.42) PTGIRALDH1A1F10PRSS1SMN1; SMN2
SCHEMBL28875780 0.85 F10 (0.39) F10PRSS1KMT2AMEN1
SCHEMBL19975134 0.83 PTGIR (0.40) PTGIRALDH1A1F10PRSS1KMT2A
SCHEMBL19974683 0.81 PTGIR (0.42) PTGIRALDH1A1KMT2AMEN1
SCHEMBL19975353 0.81 BCHE (0.45) ALDH1A1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL19974728 0.81 BCHE (0.42) PTGIRALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL19975543 0.80 HPGD (0.49) ALDH1A1KMT2AMEN1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C PTGIR 540/4885ALDH1A1 2271/4885F10 1167/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C PTGIR 679/4885ALDH1A1 2673/4885F10 1141/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C PTGIR 540/4885ALDH1A1 2271/4885F10 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.