SCHEMBL19974988

SCHEMBL19974988

Cc1ccccc1N(C=O)[C@H](C)C(=O)C(=O)NCC1CC1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 1/20 0.35
MAPK14 Q16539 5/20 0.34
SIGMAR1 Q99720 1/20 0.34
PTGIR P43119 3/20 0.34
CNR1 P21554 1/20 0.34
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975397 1.00 L3MBTL1 (0.39) L3MBTL1MAPTLMNAMAPK14SIGMAR1
SCHEMBL19975382 1.00 L3MBTL1 (0.39) L3MBTL1MAPTLMNAMAPK14SIGMAR1
SCHEMBL19974799 0.87 SMN1; SMN2 (0.35) L3MBTL1SIGMAR1PTGIROPRD1OPRK1
SCHEMBL19974871 0.87 MEN1 (0.39) L3MBTL1PTGIRCNR1CYP2C19ALDH1A1
SCHEMBL19975130 0.85 HPGD (0.42) L3MBTL1MAPTLMNAPTGIRALDH1A1
SCHEMBL21176277 0.84 PTGIR (0.41) SIGMAR1PTGIRCYP2C19
SCHEMBL19975377 0.81 HPGD (0.50) L3MBTL1MAPTLMNAALDH1A1GAA
SCHEMBL19974932 0.81 L3MBTL1 (0.38) L3MBTL1MAPTLMNAALDH1A1GAA
SCHEMBL19975208 0.80 EPHX1 (0.43) L3MBTL1OPRK1ALDH1A1GAASMN1; SMN2
SCHEMBL19975136 0.80 EPHX1 (0.40) L3MBTL1PTGIROPRK1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C L3MBTL1 1238/4885MAPT 4561/4885LMNA 1909/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C L3MBTL1 1885/4885MAPT 4673/4885LMNA 2058/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C L3MBTL1 1238/4885MAPT 4561/4885LMNA 1909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.