SCHEMBL19975211

SCHEMBL19975211

[O]S(=O)c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
HSD17B10 Q99714 4/20 0.43
CYP2A6 P11509 3/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP1A2 P05177 4/20 0.41
HPGD P15428 2/20 0.41
CYP3A4 P08684 1/20 0.41
KEAP1 Q14145 1/20 0.41
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
HPRT1 P00492 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 1/20 0.39
PAX8 Q06710 1/20 0.38
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL347056 0.79 CYP1A2 (0.44) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL30785066 0.79 CYP1A2 (0.44) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28136648 0.77 CYP1A2 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28421820 0.77 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Ammonia Solution, Strong SCHEMBL21314237 0.77 CYP1A2 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1583760 0.77 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL29850141 0.77 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1583765 0.77 CYP1A2 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Formaldehyde SCHEMBL11755336 0.76 CYP1A2 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL6339025 0.74 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018167677-A1 NOVEL DITHIOLANE COMPOUND OR A SALT OR AN N-OXIDE AND USE THEREOF OAT & IIL INDIA LABORATORIES PRIVATE LIMITED (IN) 2018-09-20 WO disclosed
WO-2018138692-A1 NOVEL FUNGICIDAL CARBAMATE COMPOUNDS INSECTICIDES (INDIA) LIMITED (IN) 2018-08-02 WO disclosed
WO-2018051252-A2 NOVEL AMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND MITICIDE INSECTICIDES (INDIA) LIMITED (IN) 2018-03-22 WO disclosed