SCHEMBL28136648

SCHEMBL28136648

O=S(O)c1cccc2ccccc12.[SrH2]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
ALDH1A1 P00352 4/20 0.40
CYP2A6 P11509 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
MMP3 P08254 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
KEAP1 Q14145 1/20 0.38
ACP3 P15309 1/20 0.37
PTPN1 P18031 1/20 0.37
CDC25B P30305 1/20 0.37
PLK1 P53350 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30785066 0.98 CYP1A2 (0.44) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL347056 0.98 CYP1A2 (0.44) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL1583765 0.96 CYP1A2 (0.43) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
Ammonia Solution, Strong SCHEMBL21314237 0.96 CYP1A2 (0.43) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
Formaldehyde SCHEMBL11755336 0.94 CYP1A2 (0.41) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL21314245 0.84 CDYL (0.44) CYP1A2ALDH1A1TDP1TSHRKDM4E
SCHEMBL4649800 0.82 ALDH1A1 (0.37) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL21314240 0.79 ALDH1A1 (0.42) CYP1A2ALDH1A1CYP2A6TDP1KDM4E
N-Benzylmethylamine SCHEMBL28137345 0.79 KDM4E (0.49) CYP1A2TSHRKDM4ECYP3A4ACP3
SCHEMBL19975211 0.77 ALDH1A1 (0.43) CYP1A2NR4A1NR4A2NR4A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106535815-B Reactive micro-applicator with metal-containing additives for applying dental adhesives 古莎有限公司 2020-05-29 CN disclosed
CN-106535815-A Reactive micro-applicator with metal-containing additives for applying dental adhesives 贺利氏古萨有限公司 2017-03-22 CN disclosed