Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975423 | 1.00 | EPHX1 (0.39) | EPHX1ADH1BADH1CADH1ACYP2D6 | |
| SCHEMBL19974862 | 0.89 | ADH1B (0.46) | EPHX1ADH1BADH1CADH1ACYP2D6 | |
| SCHEMBL19975527 | 0.86 | ADH1C (0.46) | EPHX1ADH1BADH1CADH1ACYP2D6 | |
| SCHEMBL21176290 | 0.86 | KMT2A (0.42) | EPHX1ADH1BADH1CADH1ASMN1; SMN2 | |
| SCHEMBL30063422 | 0.86 | KMT2A (0.42) | EPHX1ADH1BADH1CADH1ASMN1; SMN2 | |
| SCHEMBL21176292 | 0.86 | KMT2A (0.42) | EPHX1ADH1BADH1CADH1ASMN1; SMN2 | |
| SCHEMBL19974956 | 0.80 | ADH1C (0.50) | EPHX1ADH1BADH1CADH1ASMN1; SMN2 | |
| SCHEMBL19975269 | 0.78 | EPHX1 (0.46) | EPHX1CYP2D6SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21176352 | 0.78 | EPHX1 (0.46) | EPHX1CYP2D6SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL19975360 | 0.77 | MEN1 (0.35) | ADH1BADH1CADH1ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512836-A1 | ANTIVIRAL COMPOUNDS | Haplogen GmbH (AT) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |