SCHEMBL19975438

SCHEMBL19975438

CC(C(O)C(=O)NCC1CCCCC1)N(C=O)c1ccncc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
ALDH1A1 P00352 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
GAA P10253 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
EPHX1 P07099 1/20 0.40
EPHX2 P34913 1/20 0.40
BCHE P06276 3/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
NAMPT P43490 1/20 0.38
KDM4C Q9H3R0 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19974994 0.89 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL21176166 0.89 BCHE (0.46) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL19975353 0.87 BCHE (0.45) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL21176168 0.86 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL19974728 0.85 BCHE (0.42) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL19975274 0.82 PTGIR (0.41) ALDH1A1GAAMEN1KMT2ABCHE
SCHEMBL19974807 0.82 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL19975143 0.81 PTGIR (0.43) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL19974938 0.81 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1
SCHEMBL19975134 0.81 PTGIR (0.40) SMN1; SMN2ALDH1A1L3MBTL1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C SMN1; SMN2 706/4885ALDH1A1 2271/4885L3MBTL1 1238/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C SMN1; SMN2 1086/4885ALDH1A1 2673/4885L3MBTL1 1885/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C SMN1; SMN2 706/4885ALDH1A1 2271/4885L3MBTL1 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.