SCHEMBL19975644

SCHEMBL19975644

CCCC[P+](c1ccccc1)(c1ccccc1)c1cccc(S(=O)(=O)[O-])c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.40
MMP1 P03956 4/20 0.39
MMP7 P09237 4/20 0.39
MMP12 P39900 4/20 0.39
MMP13 P45452 4/20 0.39
ACE P12821 3/20 0.39
HIF1A Q16665 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 1/20 0.37
PSIP1 O75475 1/20 0.36
TRAP1 Q12931 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyltriphenylphosphonium SCHEMBL6928248 0.84 CNR2 (0.45) NR1I2MMP1MMP7MMP12MMP13
Butyltriphenylphosphonium SCHEMBL3950032 0.81 S1PR3 (0.40) NR1I2MMP1MMP7MMP12MMP13
Butyltriphenylphosphonium SCHEMBL28694042 0.81 CHRNA7 (0.48) NR1I2MMP1MMP13TRAP1KMT2A
Butyltriphenylphosphonium SCHEMBL31425590 0.80 NR1I2 (0.39) NR1I2MMP1MMP7MMP12MMP13
Butyltriphenylphosphonium SCHEMBL1804186 0.79 HIF1A (0.44) MMP1MMP7MMP12MMP13ACE
SCHEMBL9675753 0.79 NR1I2 (0.48) NR1I2HIF1ASMN1; SMN2ALDH1A1TRAP1
SCHEMBL9634519 0.79 NR1I2 (0.48) NR1I2HIF1ASMN1; SMN2ALDH1A1TRAP1
Sulfuric Acid SCHEMBL21933060 0.79 TRAP1 (0.47) NR1I2HIF1AALDH1A1TRAP1CYP1A2
SCHEMBL9634528 0.78 NR1I2 (0.40) NR1I2TDP1ALDH1A1TRAP1CYP1A2
Butyltriphenylphosphonium SCHEMBL8375252 0.78 PTGS2 (0.47) NR1I2MMP1MMP7MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920084-B2 Ionic tags for synthesis of oligoribonucleotides THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2018-03-20 US disclosed