Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975600 | 0.95 | CHRM3 (0.40) | KDM5CKDM4CCHRM3KMT2AMEN1 | |
| SCHEMBL19975749 | 0.94 | KMT2A (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL19975595 | 0.89 | TDP1 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL19975603 | 0.86 | PHGDH (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL19975750 | 0.84 | TDP1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2SLC6A2 | |
| SCHEMBL19975602 | 0.81 | GPR119 (0.43) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL19975594 | 0.80 | KMT2A (0.50) | KMT2AALDH1A1SMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL19975781 | 0.79 | ALDH1A1 (0.39) | ALDH1A1SIGMAR1SLC29A1KDM4ELMNA | |
| SCHEMBL19975596 | 0.78 | JMJD6 (0.49) | KDM5CKDM4CKMT2AMEN1ALDH1A1 | |
| SCHEMBL19975605 | 0.78 | KDM5C (0.38) | KDM5CKDM4CCHRM3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920082-B2 | Water-soluble complexing agents and corresponding lanthanide complexes | CISBO BIOASSAYS (FR) | 2018-03-20 | — | — | US | disclosed |