Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.48 |
| ▸ | F3 | P13726 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | FABP3 | P05413 | 2/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975925 | 0.96 | SMN1; SMN2 (0.59) | SMN1; SMN2NAAAF7F3PPARG | |
| SCHEMBL8708433 | 0.89 | SMN1; SMN2 (0.68) | SMN1; SMN2NAAA | |
| SCHEMBL8709262 | 0.89 | SMN1; SMN2 (0.68) | SMN1; SMN2NAAA | |
| SCHEMBL8709259 | 0.89 | SMN1; SMN2 (0.68) | SMN1; SMN2NAAA | |
| SCHEMBL8708430 | 0.89 | SMN1; SMN2 (0.68) | SMN1; SMN2NAAA | |
| SCHEMBL131852 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EF7F3PPARG | |
| SCHEMBL130753 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EF7F3PPARG | |
| SCHEMBL130986 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EF7F3PPARG | |
| SCHEMBL12640292 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4EF7F3PPARG | |
| SCHEMBL25076708 | 0.83 | NAAA (0.45) | NAAAALDH1A1KDM4EF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512449-B1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | UNIV BRITISH COLUMBIA (CA) | 2019-08-07 | — | — | EP | disclosed |
| US-9920028-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-03-20 | — | — | US | disclosed |