Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975948 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ATMSMN1; SMN2RBP4ADORA3 | |
| SCHEMBL24701188 | 0.75 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2POLBLMNANPSR1 | |
| SCHEMBL19703868 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19171550 | 0.69 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2POLBLMNAGAA | |
| SCHEMBL15491745 | 0.66 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2RBP4POLBLMNA | |
| SCHEMBL19698270 | 0.65 | NPC1 (0.50) | ALDH1A1ATMSMN1; SMN2LMNA | |
| SCHEMBL674446 | 0.64 | LMNA (0.68) | ALDH1A1ATMSMN1; SMN2POLBLMNA | |
| SCHEMBL18193499 | 0.64 | ALDH1A1 (0.56) | ALDH1A1ATMSMN1; SMN2POLBLMNA | |
| SCHEMBL13472164 | 0.63 | LMNA (0.53) | ALDH1A1ATMSMN1; SMN2POLBLMNA | |
| SCHEMBL26448356 | 0.63 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920085-B2 | Boronic acid conjugates of oligonucleotide analogues | SAREPTA THERAPEUTICS, INC. (US) | 2018-03-20 | — | — | US | disclosed |