SCHEMBL19976024

SCHEMBL19976024

CCC(C)COC(=O)CC1CC(=O)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
HTR2C P28335 5/20 0.38
MAPT P10636 2/20 0.37
IDO1 P14902 1/20 0.34
TSHR P16473 2/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HHAT Q5VTY9 1/20 0.33
FFAR1 O14842 1/20 0.33
SLC25A5 P05141 1/20 0.33
POLB P06746 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19976028 0.84 CYP1A2 (0.42) CYP1A2HTR2CMAPTTSHRSIGMAR1
SCHEMBL17540282 0.82 PRSS1 (0.50) CYP1A2HTR2CMAPTTSHRCYP3A4
SCHEMBL19976023 0.82 TSHR (0.48) CYP1A2HTR2CMAPTTSHRCYP3A4
SCHEMBL17540291 0.81 CYP1A2 (0.36) CYP1A2HTR2CMAPTIDO1SIGMAR1
SCHEMBL17400432 0.79 HTR2C (0.47) CYP1A2HTR2CSIGMAR1CYP2D6
SCHEMBL17400444 0.78 ALDH1A1 (0.46) MAPTALDH1A1
SCHEMBL21978272 0.77 GLA (0.48) HTR2CMAPTSIGMAR1CYP3A4CYP2C9
SCHEMBL17400434 0.73 ALDH1A1 (0.47) MAPTSIGMAR1CYP2D6FFAR1POLB
SCHEMBL30978693 0.72 TP53 (0.46) CYP1A2HTR2CMAPTTSHRSIGMAR1
SCHEMBL569181 0.72 TP53 (0.46) CYP1A2HTR2CMAPTTSHRSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923143-B2 Fullerene derivative, organic solar cell using same, and manufacturing method thereof LG CHEM, LTD. (KR) 2018-03-20 US disclosed