SCHEMBL19976028

SCHEMBL19976028

CCC(C)OC(=O)CC1CC(=O)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 2/20 0.42
TSHR P16473 2/20 0.42
CYP2C19 P33261 2/20 0.42
HSD17B10 Q99714 1/20 0.42
HTR2C P28335 5/20 0.40
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.36
SLC25A5 P05141 1/20 0.35
GLS O94925 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19976023 0.88 TSHR (0.48) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL17400444 0.86 ALDH1A1 (0.46) MAPTKMT2A
SCHEMBL19976024 0.84 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL17400432 0.82 HTR2C (0.47) CYP1A2HTR2CCYP2D6SIGMAR1
SCHEMBL17540282 0.76 PRSS1 (0.50) CYP1A2CYP3A4TSHRHSD17B10HTR2C
SCHEMBL569181 0.75 TP53 (0.46) CYP1A2TSHRHTR2CMAPTGLS
SCHEMBL30978693 0.75 TP53 (0.46) CYP1A2TSHRHTR2CMAPTGLS
SCHEMBL17540291 0.75 CYP1A2 (0.36) CYP1A2HTR2CMAPTGLSSIGMAR1
SCHEMBL21978272 0.75 GLA (0.48) CYP3A4CYP2C9CYP2C19HTR2CMAPT
SCHEMBL568436 0.75 HTR2C (0.49) HTR2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923143-B2 Fullerene derivative, organic solar cell using same, and manufacturing method thereof LG CHEM, LTD. (KR) 2018-03-20 US disclosed