SCHEMBL19976145

SCHEMBL19976145

COC(C)OC(=O)C(C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
MME P08473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12413027 0.81 SMN1; SMN2 (0.39) MMESMN1; SMN2
SCHEMBL1728121 0.77 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL3020915 0.75 TP53 (0.36) TP53SMN1; SMN2
SCHEMBL1833108 0.74
SCHEMBL225761 0.74
SCHEMBL9764287 0.73 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL26939374 0.73 TP53 (0.35) TP53
SCHEMBL984063 0.71 TSHR (0.36) SMN1; SMN2
SCHEMBL8712260 0.71 TP53 (0.42) TP53SMN1; SMN2
SCHEMBL36130 0.71 TP53 (0.42) TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11480577-B2 Biopsy methods and devices INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2022-10-25 US disclosed
US-10753942-B2 Methods to detect remnant cancer cells INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2020-08-25 US disclosed
US-20200150127-A1 BIOPSY METHODS AND DEVICES INDICATOR SYSTEMS INTERNATIONAL, INC. 2020-05-14 US disclosed
US-20190107543-A1 METHODS TO DETECT REMNANT CANCER CELLS INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2019-04-11 US disclosed
US-10239891-B2 Compositions to detect remnant cancer cells INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2019-03-26 US disclosed
US-20180328933-A1 BIOPSY METHODS AND DEVICES INDICATOR SYSTEMS INTERNATIONAL, INC. 2018-11-15 US disclosed
US-20180327424-A1 COMPOSITIONS TO DETECT REMNANT CANCER CELLS INDICATOR SYSTEMS INTERNATIONAL, INC. 2018-11-15 US disclosed
US-9926334-B1 2018-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11480577-B2 Biopsy methods and devices MKI67, RNASE1, CD63 TP53 13/4885SLC1A3 4813/4885SLC1A2 4863/4885
US-20180327424-A1 COMPOSITIONS TO DETECT REMNANT CANCER CELLS MKI67, TP53, RNASE1 TP53 2/4885SLC1A3 4876/4885SLC1A2 4872/4885
US-10239891-B2 Compositions to detect remnant cancer cells MKI67, TP53, RNASE1 TP53 2/4885SLC1A3 4876/4885SLC1A2 4872/4885
US-20180328933-A1 BIOPSY METHODS AND DEVICES MKI67, RNASE1, CD63 TP53 13/4885SLC1A3 4813/4885SLC1A2 4863/4885
US-20200150127-A1 BIOPSY METHODS AND DEVICES MKI67, RNASE1, CD63 TP53 13/4885SLC1A3 4813/4885SLC1A2 4863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.