SCHEMBL8712260

SCHEMBL8712260

CC(C(=O)O)C(=O)OOC(=O)C(C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.42
SLC7A5 Q01650 2/20 0.35
KMT2A Q03164 1/20 0.31
GABRR1 P24046 2/20 0.31
RNPEP Q9H4A4 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24725871 0.86 TP53 (0.36) TP53SLC7A5KMT2ASMN1; SMN2
SCHEMBL36130 0.81 TP53 (0.42) TP53SLC7A5GABRR1RNPEPSMN1; SMN2
SCHEMBL9806941 0.80 TP53 (0.32) TP53
SCHEMBL6296205 0.79
SCHEMBL225761 0.79
SCHEMBL27881916 0.79 TP53 (0.40) TP53SLC7A5CYP1A2
SCHEMBL28738930 0.77
SCHEMBL17622448 0.77
SCHEMBL28445868 0.77
Methylmalonic Acid SCHEMBL27881917 0.75 TP53 (0.57) TP53SLC7A5GABRR1RNPEPCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422952-A Resin combination and surface protection film 大金工业株式会社 2019-03-05 CN disclosed
US-5776294-A CROSSLINKED WITH METAL SALT OF AN UNSATURATED ACID SARTOMER COMPANY (US) 1998-07-07 US disclosed
EP-0534847-B1 Plastisol compositions SARTOMER CO INC (US) 1996-12-27 EP disclosed
US-5298562-A Copolymer of ethylene-propylene and/or alpha olefin, elastomer copolymer of ethylene-propylene and/or alpha olefin SARTOMER COMPANY, INC. (US) 1994-03-29 US disclosed
EP-0534847-A1 Plastisol compositions SARTOMER COMPANY, INC. (US) 1993-03-31 EP disclosed
US-5150905-A Surface treatment of alkali metal titanate ASICS CORPORATION (JP) 1992-09-29 US disclosed
US-5141233-A Containing surface-treated fine inorganic fibers, non-sulfur vulcanizing agent; durability, compressive strength ASICS CORPORATION (JP) 1992-08-25 US disclosed
EP-0487397-A1 Curable compositions and their use for obtaining cured elastomers SARTOMER COMPANY, INC. (US) 1992-05-27 EP disclosed
US-4955966-A SURFACE TREATED INORGANIC FIBERS ASICS CORPORATION (JP) 1990-09-11 US disclosed
US-4444921-A Coated calcium carbonate in polyester/rubber molding compound PHILLIPS PETROLEUM COMPANY (US) 1984-04-24 US disclosed
US-RE31436-E VINYL MONOMER, CATALYST, FIBROUS REINFOREMENT, SYNTHETIC LUBRICANT, THICKENER, FILLER, MILLING PHILLIPS PETROLEUM COMPANY (US) 1983-11-01 US disclosed
US-4158654-A IMPACT STRENGTH, GOOD SURFACE FINISH PHILLIPS PETROLEUM COMPANY (US) 1979-06-19 US disclosed
US-4020036-A Thermosetting polyester composition containing normally solid carboxy-containing diene polymer PHILLIPS PETROLEUM COMPANY (US) 1977-04-26 US disclosed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US disclosed