SCHEMBL1997638

SCHEMBL1997638

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nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.41
CD274 Q9NZQ7 3/20 0.40
PDCD1LG2 Q9BQ51 2/20 0.40
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 2/20 0.37
VSIR Q9H7M9 3/20 0.36
TP53 P04637 1/20 0.36
SDCBP O00560 1/20 0.35
SDC2 P34741 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1997636 1.00 MME (0.41) MMECD274PDCD1LG2CA2CA1
SCHEMBL4550632 1.00 MME (0.41) MMECD274PDCD1LG2CA2CA1
SCHEMBL6314356 0.84 NPSR1 (0.50) NPSR1ALDH1A1SDCBPSDC2SMN1; SMN2
SCHEMBL15231611 0.84 NPSR1 (0.50) NPSR1ALDH1A1SDCBPSDC2SMN1; SMN2
SCHEMBL4195957 0.83 CYP2C9 (0.43) MMECD274PDCD1LG2CA2CA1
SCHEMBL4195960 0.83 CYP2C9 (0.43) MMECD274PDCD1LG2CA2CA1
SCHEMBL6308358 0.83 MME (0.41) MMECD274PDCD1LG2CA2CA1
SCHEMBL23408858 0.81 CA2 (0.41) MMECD274PDCD1LG2CA2CA1
SCHEMBL11106438 0.81 CA2 (0.41) MMECD274PDCD1LG2CA2CA1
SCHEMBL3868722 0.81 CA2 (0.41) MMECD274PDCD1LG2CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11992518-B2 Molecular vaccines for infectious disease AGILENT TECHNOLOGIES, INC. (US) 2024-05-28 US disclosed
US-10968269-B1 MHC multimers in borrelia diagnostics and disease AGILENT TECHNOLOGIES, INC. (US) 2021-04-06 US disclosed
US-20210047383-A1 MHC Multimers in Borrelia Diagnostics and Disease DAKO DENMARK APS (DK) 2021-02-18 US disclosed
US-20200347103-A1 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS AGILENT TECHNOLOGIES INC (US) 2020-11-05 US disclosed
US-10611818-B2 MHC multimers in tuberculosis diagnostics, vaccine and therapeutics AGILENT TECHNOLOGIES, INC. (US) 2020-04-07 US disclosed
US-20190314471-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES, INC. 2019-10-17 US disclosed
US-10369204-B2 Molecular vaccines for infectious disease DAKO DENMARK A/S (DK) 2019-08-06 US disclosed
CN-104583235-B Antibodies comprising site-specific unnatural amino acid residues, methods of making and using the same 苏特罗生物制药公司 2019-03-01 CN disclosed
US-20120258126-A1 Molecular Vaccines for Infectious Disease DAKO DENMARK A/S (DK) 2012-10-11 US disclosed
US-20110318380-A1 MHC Multimers in Cancer Vaccines and Immune Monitoring DAKO DENMARK A/S (DK) 2011-12-29 US disclosed
EP-0996455-A4 ALPHA-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF SLOAN KETTERING INSTITUTEFOR C (US) 2005-06-08 EP disclosed
EP-1091751-A4 TRIMERIC ANTIGENIC O-LINKED GLYCOPEPTIDE CONJUGATES, METHODS OF PREPARATION AND USES THEREOF SLOAN KETTERING INSTITUTEFOR C (US) 2005-01-19 EP disclosed
US-20040102607-A1 Trimeric antigenic O-linked glycopeptide conjugates, methods of preparation and uses thereof DANISHEFSKY SAMUEL J (US) 2004-05-27 US disclosed
US-6660714-B1 Anticancer agents SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH 2003-12-09 US disclosed
EP-1091751-A1 TRIMERIC ANTIGENIC O-LINKED GLYCOPEPTIDE CONJUGATES, METHODS OF PREPARATION AND USES THEREOF Sloan-Kettering Institute For Cancer Research (US) 2001-04-18 EP disclosed
EP-0996455-A1 $g(a)-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF Sloan-Kettering Institute For Cancer Research (US) 2000-05-03 EP disclosed
WO-1999048515-A9 TRIMERIC ANTIGENIC O-LINKED GLYCOPEPTIDE CONJUGATES, METHODS OF PREPARATION AND USES THEREOF SLOAN KETTERING INST CANCER (US) 1999-11-25 WO disclosed
WO-1999048515-A1 TRIMERIC ANTIGENIC O-LINKED GLYCOPEPTIDE CONJUGATES, METHODS OF PREPARATION AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1999-09-30 WO disclosed
WO-1998046246-A1 α-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1998-10-22 WO disclosed
US-4861755-A Peptides with vasorelaxant, natriuretic and diuretic effects a process for their preparation, agents containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102607-A1 Trimeric antigenic O-linked glycopeptide conjugates, methods of preparation and uses thereof MUC1, OSTC, SIGLEC7 MME 1210/4885CD274 715/4885PDCD1LG2 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.