Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PHGDH | O43175 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358981 | 0.90 | ALDH1A1 (0.41) | ALDH1A1PHGDHL3MBTL1RAB9AMAPT | |
| SCHEMBL16964699 | 0.89 | PHGDH (0.42) | ALDH1A1PHGDHL3MBTL1RAB9AMAPT | |
| SCHEMBL16964038 | 0.89 | PHGDH (0.44) | ALDH1A1PHGDHL3MBTL1RAB9AMAPT | |
| SCHEMBL16991037 | 0.88 | PHGDH (0.46) | ALDH1A1PHGDHL3MBTL1RAB9AMAPT | |
| SCHEMBL18359009 | 0.85 | POLB (0.47) | ALDH1A1PHGDHL3MBTL1RAB9AMEN1 | |
| SCHEMBL16991026 | 0.84 | PHGDH (0.41) | ALDH1A1PHGDHL3MBTL1RAB9ASGK1 | |
| SCHEMBL17000510 | 0.83 | PHGDH (0.40) | ALDH1A1PHGDHL3MBTL1RAB9AMAPT | |
| SCHEMBL16991041 | 0.82 | HDAC3 (0.44) | ALDH1A1PHGDHMAPTHDAC3HDAC4 | |
| SCHEMBL16963677 | 0.81 | CDK5 (0.41) | ALDH1A1PHGDHL3MBTL1RAB9AMAPT | |
| SCHEMBL19976448 | 0.81 | ADRB3 (0.42) | PHGDHMAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |