Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | GIPR | P48546 | 1/20 | 0.42 |
| ▸ | DDT | P30046 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NME4 | O00746 | 1/20 | 0.40 |
| ▸ | GCDH | Q92947 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976445 | 0.86 | MIF (0.53) | MIFP2RY14OPRD1SIGMAR1MLYCD | |
| SCHEMBL16964139 | 0.85 | AR (0.46) | MIFP2RY14OPRD1SIGMAR1MLYCD | |
| SCHEMBL16963676 | 0.84 | NOTUM (0.59) | MIFMAPT | |
| SCHEMBL17000543 | 0.84 | MIF (0.48) | MIFP2RY14OPRD1SIGMAR1DGAT1 | |
| SCHEMBL16996775 | 0.84 | NOTUM (0.53) | MIFP2RY14OPRD1SIGMAR1MLYCD | |
| SCHEMBL19976501 | 0.83 | MIF (0.43) | MIFP2RY14OPRD1SIGMAR1MLYCD | |
| SCHEMBL16964675 | 0.83 | MIF (0.50) | MIFP2RY14OPRD1SIGMAR1MLYCD | |
| SCHEMBL16991070 | 0.82 | MIF (0.52) | MIFP2RY14OPRD1SIGMAR1DGAT1 | |
| SCHEMBL16964546 | 0.82 | DDX3X (0.53) | MIFP2RY14OPRD1SIGMAR1RAB9A | |
| SCHEMBL16964165 | 0.81 | MIF (0.46) | MIFP2RY14OPRD1SIGMAR1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |