Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.43 |
| ▸ | DDX3X | O00571 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16963676 | 0.89 | NOTUM (0.59) | MIFNOTUMMAOAMAOBFOLH1 | |
| SCHEMBL16964675 | 0.88 | MIF (0.50) | MIFNOTUMDGAT1MAOAMAOB | |
| SCHEMBL16964546 | 0.87 | DDX3X (0.53) | MIFNOTUMMAOAMAOBFOLH1 | |
| SCHEMBL16991070 | 0.87 | MIF (0.52) | MIFNOTUMDGAT1MAOAMAOB | |
| SCHEMBL16964548 | 0.86 | DDX3X (0.56) | MIFDGAT1FOLH1DDX3X | |
| SCHEMBL19976444 | 0.86 | MIF (0.46) | MIFDGAT1P2RY14OPRD1SIGMAR1 | |
| SCHEMBL19976510 | 0.84 | FOLH1 (0.47) | MIFDGAT1FOLH1DDX3X | |
| SCHEMBL16964139 | 0.83 | AR (0.46) | MIFDGAT1P2RY14OPRD1SIGMAR1 | |
| SCHEMBL17000543 | 0.82 | MIF (0.48) | MIFDGAT1MAOAMAOBP2RY14 | |
| SCHEMBL16996775 | 0.82 | NOTUM (0.53) | MIFNOTUMDGAT1P2RY14OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |