Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | SLC9A3 | P48764 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18155871 | 0.85 | CA2 (0.42) | CA2CA12CA1CA4CA9 | |
| SCHEMBL4270081 | 0.76 | TSHR (0.46) | CA2CA12CA1CA4CA9 | |
| SCHEMBL19455426 | 0.75 | GAA (0.45) | CA2CA12CA1CA4CA9 | |
| SCHEMBL25370361 | 0.75 | CA2 (0.36) | CA2CA12CA1CA4CA9 | |
| SCHEMBL16156327 | 0.75 | TSHR (0.35) | CA2CA12CA1CA4CA9 | |
| SCHEMBL16983217 | 0.74 | TSHR (0.38) | CA2CA12CA1CA4CA9 | |
| SCHEMBL21415394 | 0.74 | CA2 (0.44) | CA2CA12CA1CA4CA9 | |
| SCHEMBL24976899 | 0.74 | CA2 (0.47) | CA2CA12CA1CA4CA9 | |
| SCHEMBL19432362 | 0.74 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL16329783 | 0.74 | CA2 (0.34) | CA2CA12CA1CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919055-B2 | Sugar-linker-drug conjugates | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |