Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21415394 | 0.89 | CA2 (0.44) | CA2CA12CA1CA4CA9 | |
| SCHEMBL4270081 | 0.86 | TSHR (0.46) | CA2CA12CA1CA4CA9 | |
| SCHEMBL19455426 | 0.86 | GAA (0.45) | CA2CA12CA1CA4CA9 | |
| SCHEMBL23822616 | 0.85 | CA2 (0.42) | CA2CA12CA1CA4CA9 | |
| SCHEMBL24976899 | 0.85 | CA2 (0.47) | CA2CA12CA1CA4CA9 | |
| SCHEMBL16983217 | 0.85 | TSHR (0.38) | CA2CA12CA1CA4CA9 | |
| SCHEMBL19976490 | 0.85 | CA2 (0.33) | CA2CA12CA1CA4CA9 | |
| SCHEMBL19560737 | 0.84 | NAAA (0.47) | CA2CA12CA1CA4CA9 | |
| SCHEMBL14258541 | 0.84 | GAA (0.50) | CA2CA12CA1CA4CA9 | |
| SCHEMBL16329534 | 0.84 | SMN1; SMN2 (0.46) | CA2CA12CA1CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2901160-B1 | METHOD FOR SPECIFICALLY DETECTING A MATRIX METALLOPROTEINASE (MMP) WHICH IS ONLY OF INTEREST IN THE ACTIVE FORM THEREOF, IN A SAMPLE | COMMISSARIAT À L EN ATOMIQUE ET AUX EN ALTERNATIVES (FR) | 2016-10-19 | — | — | EP | disclosed |