Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956179 | 0.82 | ALDH1A1 (0.64) | MAPTHPGDALDH1A1HTTRAB9A | |
| SCHEMBL19626644 | 0.82 | HPGD (0.65) | MAPTHPGDALDH1A1HTTRAB9A | |
| SCHEMBL18358985 | 0.81 | ALDH1A1 (0.62) | MAPTHPGDALDH1A1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL16991024 | 0.79 | ALDH1A1 (0.62) | MAPTHPGDALDH1A1HTTRAB9A | |
| SCHEMBL16601604 | 0.79 | MAPT (0.77) | MAPTHPGDALDH1A1HTTNPSR1 | |
| SCHEMBL16964226 | 0.79 | ALDH1A1 (0.57) | MAPTHPGDALDH1A1HTTRAB9A | |
| SCHEMBL16964049 | 0.78 | MAPT (0.54) | MAPTHPGDALDH1A1HTTRAB9A | |
| SCHEMBL16991074 | 0.78 | MAPT (0.54) | MAPTHPGDALDH1A1HTTRAB9A | |
| SCHEMBL19627024 | 0.78 | ALDH1A1 (0.72) | MAPTHPGDALDH1A1HTTRAB9A | |
| SCHEMBL16964202 | 0.77 | MAPT (0.53) | MAPTHPGDALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |