Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CPB1 | P15086 | 1/20 | 0.61 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13251388 | 0.99 | HTT (0.65) | TGM2HTTCPB1CPB2FOLH1 | |
| SCHEMBL10032568 | 0.94 | HTT (0.67) | TGM2HTTCPB1CPB2FOLH1 | |
| Ammonia Solution, Strong SCHEMBL8060380 | 0.93 | HTT (0.65) | TGM2HTTCPB1CPB2FOLH1 | |
| SCHEMBL7378562 | 0.88 | LMNA (0.65) | HTTCPB1CPB2LMNASMN1; SMN2 | |
| SCHEMBL15346534 | 0.88 | HTT (0.79) | TGM2HTTFOLH1LMNASMN1; SMN2 | |
| SCHEMBL9340146 | 0.88 | HTT (0.79) | TGM2HTTFOLH1LMNASMN1; SMN2 | |
| SCHEMBL9874334 | 0.88 | HTT (0.79) | TGM2HTTFOLH1LMNASMN1; SMN2 | |
| SCHEMBL24845248 | 0.88 | DPP8 (0.63) | TGM2HTTCPB1CPB2FOLH1 | |
| SCHEMBL13471242 | 0.88 | FOLH1 (0.62) | TGM2HTTCPB1CPB2FOLH1 | |
| SCHEMBL17250893 | 0.88 | FOLH1 (0.62) | TGM2HTTCPB1CPB2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919026-B2 | Vasopressin formulations for use in treatment of hypotension | PAR PHARMACEUTICAL, INC. (US) | 2018-03-20 | — | — | US | disclosed |