Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 11/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | PKLR | P30613 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976581 | 0.81 | PKM (0.56) | PKMLMNARAB9AMEN1KMT2A | |
| SCHEMBL1722758 | 0.76 | PKM (1.00) | PKMLMNAPKLRRAB9ANPC1 | |
| SCHEMBL1722280 | 0.73 | PKM (0.79) | PKMLMNAPKLRRAB9ANPC1 | |
| SCHEMBL10064231 | 0.71 | PKM (0.65) | PKMLMNAPKLRRAB9ANPC1 | |
| SCHEMBL1722457 | 0.70 | PKM (0.65) | PKMLMNAPKLRRAB9ANPC1 | |
| SCHEMBL1725568 | 0.70 | PKM (1.00) | PKMLMNAPKLRRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL28348986 | 0.70 | PKM (0.69) | PKMLMNAPKLRRAB9ANPC1 | |
| SCHEMBL29483533 | 0.70 | PKM (0.84) | PKMLMNAPKLRRAB9ANPC1 | |
| SCHEMBL15830697 | 0.70 | PKM (1.00) | PKMLMNAPKLRRAB9ANPC1 | |
| SCHEMBL1726834 | 0.69 | PKM (1.00) | PKMLMNAPKLRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920073-B2 | Compositions useful for inhibiting HIV-1 infection and methods using same | DREXEL UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |