Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270641 | 0.83 | CNR1 (0.69) | PKMKMT2ALMNATSHRUSP2 | |
| SCHEMBL6177993 | 0.82 | LMNA (0.67) | PKMKMT2AMEN1RAB9ALMNA | |
| SCHEMBL19976588 | 0.81 | PKM (0.69) | PKMKMT2AMEN1RAB9ALMNA | |
| SCHEMBL18134604 | 0.75 | MCOLN3 (0.83) | PKMKMT2AMEN1RAB9ALMNA | |
| SCHEMBL18711449 | 0.75 | PKM (0.74) | PKMKMT2AMEN1RAB9ALMNA | |
| SCHEMBL10064233 | 0.74 | PKM (0.72) | PKMKMT2AMEN1RAB9ALMNA | |
| SCHEMBL12341270 | 0.73 | PKM (0.71) | PKMKMT2AMEN1LMNATSHR | |
| SCHEMBL3169939 | 0.72 | MCOLN3 (0.97) | PKMKMT2AMEN1LMNATSHR | |
| SCHEMBL9950444 | 0.72 | PKM (1.00) | PKMKMT2AMEN1RAB9ALMNA | |
| SCHEMBL18702168 | 0.72 | PKM (0.69) | PKMKMT2AMEN1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920073-B2 | Compositions useful for inhibiting HIV-1 infection and methods using same | DREXEL UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |