SCHEMBL19976644

SCHEMBL19976644

CC(NC(=O)c1ccccc1C(F)(F)F)C(=O)c1ncc(Cl)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSS P25774 6/20 0.47
CTSK P43235 5/20 0.47
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
PTGES O14684 2/20 0.42
RECQL P46063 1/20 0.39
PTGER4 P35408 3/20 0.39
KDM4E B2RXH2 2/20 0.39
ABL1 P00519 1/20 0.38
SRC P12931 1/20 0.38
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975804 0.90 CTSS (0.46) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711957 0.85 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711959 0.85 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711958 0.85 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711837 0.84 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711839 0.84 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711871 0.84 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711840 0.84 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711764 0.83 KCNK3 (0.41) CTSSCTSKPTGESPTGER4KDM4E
SCHEMBL16711767 0.83 KCNK3 (0.41) CTSSCTSKPTGESPTGER4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920046-B2 Oxime-substituted amide compound and pest control agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-20 US disclosed