SCHEMBL19975804

SCHEMBL19975804

Cc1cnc(C(=O)C(C)NC(=O)c2ccccc2C(F)(F)F)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSS P25774 6/20 0.46
CTSK P43235 5/20 0.46
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
PTGES O14684 9/20 0.41
KCNK3 O14649 1/20 0.40
KCNK9 Q9NPC2 1/20 0.40
ABL1 P00519 1/20 0.38
SRC P12931 1/20 0.38
TRPA1 O75762 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19976644 0.90 CTSS (0.47) CTSSCTSKLMNAGAAPTGES
SCHEMBL19975808 0.87 LMNA (0.44) CTSSCTSKLMNAGAAPTGES
SCHEMBL19976646 0.82 LMNA (0.45) CTSSCTSKLMNAGAAPTGES
SCHEMBL19975802 0.80 ALDH1A1 (0.47) LMNAGAAPTGESKCNK3KCNK9
SCHEMBL15999647 0.76 PTGES (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711957 0.76 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711959 0.76 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711958 0.76 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711837 0.75 CTSS (0.41) CTSSCTSKLMNAGAAPTGES
SCHEMBL16711839 0.75 CTSS (0.41) CTSSCTSKLMNAGAAPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920046-B2 Oxime-substituted amide compound and pest control agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-20 US disclosed