Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 11/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714141 | 0.91 | GBA1 (0.44) | GBA1OPRM1 | |
| SCHEMBL16521117 | 0.79 | GBA1 (0.44) | GBA1OPRM1 | |
| SCHEMBL1831896 | 0.78 | GBA1 (0.34) | GBA1GAAHTR1ADRD2 | |
| Iodide SCHEMBL6117691 | 0.76 | GBA1 (0.33) | GBA1GAAHTR1A | |
| SCHEMBL26157149 | 0.73 | GAA (0.38) | GBA1GAA | |
| SCHEMBL22360704 | 0.72 | GBA1 (0.41) | GBA1OPRM1 | |
| SCHEMBL25681708 | 0.70 | — | — | |
| SCHEMBL25681706 | 0.70 | — | — | |
| SCHEMBL20694667 | 0.69 | GBA1 (0.36) | GBA1OPRM1 | |
| SCHEMBL22360701 | 0.69 | GBA1 (0.39) | GBA1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920086-B2 | Ruthenium-based complexes, their preparation and use as catalysts | ARLANXEO DE GMBH (DE) | 2018-03-20 | — | — | US | disclosed |