Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360706 | 0.82 | GBA1 (0.38) | GBA1OPRM1 | |
| SCHEMBL14714141 | 0.79 | GBA1 (0.44) | GBA1OPRM1ALDH1A1 | |
| SCHEMBL12208468 | 0.75 | — | — | |
| SCHEMBL22142010 | 0.74 | GBA1 (0.41) | GBA1ALDH1A1 | |
| SCHEMBL22141999 | 0.74 | GBA1 (0.41) | GBA1ALDH1A1 | |
| SCHEMBL22142003 | 0.74 | GBA1 (0.41) | GBA1ALDH1A1 | |
| SCHEMBL22142006 | 0.74 | GBA1 (0.41) | GBA1ALDH1A1 | |
| SCHEMBL19976648 | 0.72 | GBA1 (0.40) | GBA1OPRM1 | |
| SCHEMBL24035088 | 0.72 | HTR1A (0.34) | — | |
| SCHEMBL10222090 | 0.72 | HTR1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168172-A1 | CONJUGATE COMPOUNDS FOR THE DEGRADATION OF RAF | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-08-20 | — | — | WO | disclosed |