SCHEMBL19976665

SCHEMBL19976665

O=C(NCC(=O)c1ncc(C(F)(F)F)cc1Cl)c1ccccc1C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLA P06280 2/20 0.52
HPGD P15428 2/20 0.52
ALDH1A1 P00352 5/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 4/20 0.47
GAA P10253 3/20 0.47
POLB P06746 2/20 0.47
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
RAB9A P51151 1/20 0.44
PTGES O14684 1/20 0.44
LMNA P02545 2/20 0.43
RPS6KA3 P51812 1/20 0.42
HTT P42858 1/20 0.42
P2RX7 Q99572 1/20 0.42
SORT1 Q99523 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16711799 0.90 ALDH1A1 (0.51) GLAHPGDALDH1A1KDM4EGAA
SCHEMBL19975802 0.88 ALDH1A1 (0.47) HPGDALDH1A1KMT2AKDM4EGAA
SCHEMBL16711891 0.87 HPGD (0.48) GLAHPGDALDH1A1MEN1KMT2A
SCHEMBL16711893 0.87 HPGD (0.48) GLAHPGDALDH1A1MEN1KMT2A
SCHEMBL19976645 0.84 ALDH1A1 (0.47) HPGDALDH1A1KDM4EGAAPOLB
SCHEMBL16711742 0.83 ALDH1A1 (0.45) GLAHPGDALDH1A1MEN1KMT2A
SCHEMBL16711931 0.83 ALDH1A1 (0.45) GLAHPGDALDH1A1MEN1KMT2A
SCHEMBL16711744 0.83 ALDH1A1 (0.45) GLAHPGDALDH1A1MEN1KMT2A
SCHEMBL5200375 0.82 GLA (0.53) GLAHPGDALDH1A1MEN1KMT2A
SCHEMBL16711810 0.82 ALDH1A1 (0.44) GLAHPGDALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920046-B2 Oxime-substituted amide compound and pest control agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-20 US disclosed