SCHEMBL19975802

SCHEMBL19975802

Cc1cnc(C(=O)CNC(=O)c2ccccc2C(F)(F)F)c(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
PTGES O14684 5/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 1/20 0.42
KCNK3 O14649 2/20 0.41
KCNK9 Q9NPC2 2/20 0.41
POLB P06746 1/20 0.40
P2RX7 Q99572 1/20 0.39
RAB9A P51151 2/20 0.39
TP53 P04637 2/20 0.39
HPGD P15428 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16711799 0.89 ALDH1A1 (0.51) ALDH1A1PTGESLMNAGAAPOLB
SCHEMBL19976665 0.88 GLA (0.52) ALDH1A1PTGESLMNAGAAPOLB
SCHEMBL19975807 0.87 LMNA (0.45) ALDH1A1PTGESLMNAGAAKCNK3
SCHEMBL19975805 0.83 ALDH1A1 (0.45) ALDH1A1PTGESLMNAGAAKCNK3
SCHEMBL19975803 0.83 RAB9A (0.41) GAAP2RX7RAB9AHPGDSMN1; SMN2
SCHEMBL19976645 0.83 ALDH1A1 (0.47) ALDH1A1LMNAGAAPOLBP2RX7
SCHEMBL10106053 0.80 TP53 (0.48) PTGESLMNAGAAKCNK3KCNK9
SCHEMBL16711830 0.80 LMNA (0.47) ALDH1A1PTGESLMNAGAAKCNK3
SCHEMBL15999656 0.80 P2RX7 (0.43) PTGESLMNAGAAKCNK3KCNK9
SCHEMBL19975804 0.80 CTSS (0.46) PTGESLMNAGAAKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920046-B2 Oxime-substituted amide compound and pest control agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-20 US disclosed