Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.41 |
| ▸ | GSK3B | P49841 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976789 | 0.91 | GSK3B (0.42) | MAPK1GSK3BCYP1A2CDK2CDK1 | |
| SCHEMBL19976821 | 0.89 | HDAC6 (0.44) | GSK3BCYP1A2HDAC6DYRK1AHDAC1 | |
| SCHEMBL19976776 | 0.83 | GSK3B (0.48) | MAPK1GSK3BCYP1A2HDAC6DYRK1A | |
| SCHEMBL19976846 | 0.79 | KDM4E (0.42) | MAPK1GSK3BCDK2CDK1HDAC6 | |
| SCHEMBL19976729 | 0.79 | HDAC6 (0.49) | MAPK1GSK3BHDAC6HDAC1HDAC2 | |
| SCHEMBL16769265 | 0.79 | GSK3B (0.43) | GSK3BCYP1A2HDAC6DYRK1A | |
| SCHEMBL16752864 | 0.79 | GSK3B (0.46) | GSK3BCYP1A2HDAC6DYRK1A | |
| SCHEMBL16769266 | 0.79 | GSK3B (0.46) | GSK3BCYP1A2HDAC6DYRK1A | |
| SCHEMBL16752862 | 0.79 | GSK3B (0.46) | GSK3BCYP1A2HDAC6DYRK1A | |
| SCHEMBL19976866 | 0.79 | DYRK1A (0.42) | MAPK1GSK3BCYP1A2CDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |