Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 18/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976898 | 0.91 | MEN1 (0.51) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL19977097 | 0.86 | CYP2C19 (0.48) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL19976940 | 0.85 | TRPV1 (0.55) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL19977127 | 0.84 | TRPV1 (0.54) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL19977029 | 0.84 | KDM4E (0.54) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL17737359 | 0.84 | KMT2A (0.76) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL30172750 | 0.82 | MEN1 (0.58) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL16993989 | 0.82 | MEN1 (0.58) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL19976962 | 0.82 | TRPV1 (0.52) | MEN1MAPK1HTTBLMKMT2A | |
| SCHEMBL19699467 | 0.81 | LMNA (0.63) | KMT2ATRPV1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |