Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976940 | 0.88 | TRPV1 (0.55) | ALDH1A1MAPTTRPV1LMNAMEN1 | |
| SCHEMBL19977127 | 0.87 | TRPV1 (0.54) | TRPV1LMNAMEN1MAPK1HTT | |
| SCHEMBL19976895 | 0.84 | MEN1 (0.63) | TRPV1LMNAMEN1MAPK1HTT | |
| SCHEMBL16994005 | 0.83 | TRPV1 (0.55) | KDM4EALDH1A1MAPTTRPV1MEN1 | |
| SCHEMBL19976992 | 0.82 | TRPV1 (0.48) | TRPV1LMNAMEN1MAPK1HTT | |
| SCHEMBL19976908 | 0.80 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL19977017 | 0.79 | TRPV1 (0.52) | TRPV1MEN1KMT2A | |
| SCHEMBL19976962 | 0.79 | TRPV1 (0.52) | TRPV1LMNAMEN1MAPK1HTT | |
| SCHEMBL19977044 | 0.79 | TRPV1 (0.53) | ALDH1A1TRPV1LMNAMEN1HTT | |
| SCHEMBL15452706 | 0.78 | KDM4E (0.76) | KDM4EALDH1A1MAPTTRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |