Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675973 | 0.83 | MPO (0.41) | MPOSLC22A12MAPK8KDM4CPOLB | |
| SCHEMBL19976788 | 0.81 | SCN5A (0.40) | MPOSLC22A12KDM4C | |
| SCHEMBL18556901 | 0.79 | HASPIN (0.43) | SLC22A12KDM4CHTR2AHTR2CSLC6A4 | |
| Fumaric Acid SCHEMBL5678039 | 0.75 | SLC22A12 (0.47) | SLC22A12KDM4CKMOTDO2 | |
| SCHEMBL24045599 | 0.75 | ADORA2A (0.43) | SLC22A12HTR2AHTR2CMAPT | |
| SCHEMBL13106217 | 0.71 | GRM4 (0.43) | SLC22A12MAPK8KDM4CHTR2ASLC6A4 | |
| Fumaric Acid SCHEMBL5678044 | 0.68 | SLC22A12 (0.45) | SLC22A12KDM4CHTR2AHTR2CLMNA | |
| Fumaric Acid SCHEMBL5678027 | 0.68 | SLC22A12 (0.45) | SLC22A12KDM4CHTR2AHTR2CLMNA | |
| SCHEMBL5678084 | 0.68 | BRD4 (0.37) | SLC22A12POLBLMNAMEN1KMT2A | |
| SCHEMBL5678090 | 0.68 | BRD4 (0.37) | SLC22A12POLBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |