Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18556901 | 0.86 | HASPIN (0.43) | SLC22A12ESR1PLK1KDM4C | |
| SCHEMBL16682146 | 0.83 | KMO (0.46) | SCN5ASCN9ASLC22A12ESR1PLK1 | |
| SCHEMBL24045599 | 0.82 | ADORA2A (0.43) | SLC22A12ESR1PDE5A | |
| SCHEMBL19976904 | 0.81 | MPO (0.41) | SLC22A12KDM4CMPO | |
| SCHEMBL16675971 | 0.80 | SCN5A (0.41) | SCN5ASCN9ASLC22A12ESR1PLK1 | |
| SCHEMBL13106217 | 0.77 | GRM4 (0.43) | SLC22A12ESR1KDM4C | |
| Fumaric Acid SCHEMBL5678039 | 0.77 | SLC22A12 (0.47) | SLC22A12ESR1KDM4CBCL2A1 | |
| SCHEMBL13131355 | 0.73 | KDM4C (0.38) | SCN9AKDM4CMPO | |
| SCHEMBL21334032 | 0.70 | KDM4E (0.41) | ESR1PLK1PDE5AKDM4CMPO | |
| SCHEMBL16123846 | 0.70 | HTR2C (0.36) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |