SCHEMBL1997693

SCHEMBL1997693

O=c1c2ccc(c(=O)n1CCCCCO)c1c3ccc(c(=O)n(CCCCCO)c3=O)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
RGS12 O14924 1/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
PABPC1 P11940 1/20 0.46
HTT P42858 1/20 0.46
RECQL P46063 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 2/20 0.45
TSHR P16473 1/20 0.43
PARP1 P09874 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 2/20 0.41
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4017410 0.86 TDP1 (0.41) TDP1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL24440151 0.82 ALDH1A1 (0.48) TDP1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL24270356 0.82 TDP1 (0.46) TDP1ALDH1A1MEN1KMT2AHPGD
SCHEMBL6075749 0.81 TDP1 (0.59) TDP1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL15057066 0.81 TDP1 (0.59) TDP1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL54244 0.81 TDP1 (0.59) TDP1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL6751129 0.81 TDP1 (0.42) TDP1ALDH1A1KDM4EHPGDPARP1
SCHEMBL409641 0.81 TDP1 (0.45) TDP1ALDH1A1MEN1KMT2ANPC1
SCHEMBL13068795 0.80 MAOA (0.39) TDP1
SCHEMBL24634039 0.79 PIM1 (0.38) TDP1ALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444545-B1 ELECTROCHROMIC MEDIA COMPRISING CONTROLLED DIFFUSION COEFFICIENT ELECTROCHROMIC MATERIALS, AND ASSOCIATED ELECTROCHROMIC DEVICES GENTEX CORP (US) 2016-03-09 EP disclosed
US-7964328-B2 Condensation polymer photoconductive elements EASTMAN KODAK COMPANY (US) 2011-06-21 US disclosed
US-7541124-B2 Condensation polymer photoconductive elements EASTMAN KODAK COMPANY (US) 2009-06-02 US disclosed
US-20090035677-A1 CONDENSATION POLYMER PHOTOCONDUCTIVE ELEMENTS BANK OF AMERICA, N.A., AS AGENT 2009-02-05 US disclosed
US-7371492-B2 Vinyl polymer photoconductive elements EASTMAN KODAK COMPANY (US) 2008-05-13 US disclosed
EP-1915647-A1 CONDENSATION POLYMER PHOTOCONDUCTIVE ELEMENTS Eastman Kodak Company (US) 2008-04-30 EP disclosed
WO-2007024522-A1 CONDENSATION POLYMER PHOTOCONDUCTIVE ELEMENTS EASTMAN KODAK COMPANY (US) 2007-03-01 WO disclosed
US-20070042282-A1 Condensation polymer photoconductive elements EASTMAN KODAK COMPANY 2007-02-22 US disclosed
US-20070026332-A1 Vinyl polymer photoconductive elements EASTMAN KODAK COMPANY 2007-02-01 US disclosed
US-6710906-B2 Controlled diffusion coefficient electrochromic materials for use in electrochromic mediums and associated electrochromic devices GENTEX CORPORATION 2004-03-23 US disclosed
US-20020141032-A1 Controlled diffusion coefficient electrochromic materials for use in electrochromic mediums and associated electrochromic devices GENTEX CORPROATION 2002-10-03 US disclosed