Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.70 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.70 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.70 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.70 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992442 | 0.89 | TGFBR1 (0.57) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| SCHEMBL6639110 | 0.82 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| SCHEMBL2000156 | 0.77 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL2003296 | 0.77 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL2000179 | 0.77 | MAPK14 (0.63) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| SCHEMBL1995900 | 0.77 | TGFBR1 (0.60) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| Hydrochloric Acid SCHEMBL6640025 | 0.76 | TGFBR1 (0.59) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| SCHEMBL1994242 | 0.74 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL6640941 | 0.74 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1994608 | 0.74 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |