Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003296 | 0.81 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL2000156 | 0.81 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL6640941 | 0.78 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1994242 | 0.78 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1997697 | 0.77 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL6639737 | 0.73 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL2891806 | 0.72 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1994608 | 0.71 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1996761 | 0.70 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL8324311 | 0.69 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |